Possibly a slightly over-stated thread title, but nevertheless an inspiring story of perseverance:
https://www.nytimes.com/2021/04/08/health/coronavirus-mrna-kariko.html
Unfortunately the link is paywalled, but imo well worth signing up for. Surely a Nobel will be forthcoming for her and Weissman.
Had the pandemic hit a few years before, we would have been nowhere.