In reply to david100:
> not recommend acetazolamide for prophylaxis of altitude sickness
> due to the admittedly rare possibility of serious side effects.
But when out in the mountains at high altitude, _not_ taking acetazolamide could also have serious side effects.
Because difficulty in acclimatizing is about more than just discomfort.
Because time and speed matter.
. . . like . . .
Not taking acetazolamide might make one member of the party slower on ascent, and then the descent takes place later in the afternoon, and then the party is still on the slope where and when the big wet-snow avalanche comes down.
. . . like . . .
It's a stable day to move camp up to the next higher level, but some members not taking acetazolamide are not ready to move up that high. The weather forecast for the next three days is unfavorable. So the decision is stay and wait that day. Next day the weather turns worse, so the acclimatization schedule for the trip is now delayed.
Ken
P.S. Perhaps for those seriously worried about side effects from taking acetazolamide (which could be tested in a sophisticated full-support medical infrastructure at sea-level before departing for the trip), there's a simpler more important principle for avoiding unexpected risks to health:
Don't bother trying to climb mountains at high altitude in far-away regions.
Post edited at 01:31