/ Paracetamol use advice

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The Potato - on 14 May 2019

I cant take nsaids and I know they have risk associated with them anyway so would be limited to Paracetamol.

I know its commonly used to reduce temperature during illness and there is some evidence that its good for reducing core temperature when exercising in hot conditions. What im wondering however is does it have any adverse effect when exercising in the cold?

Wondering if I were to take paracetamol before a cold water swim would this affect my core temperature at all? i.e would it prevent me from getting warm enough? 

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SAF - on 14 May 2019
In reply to The Potato:

https://www.ncbi.nlm.nih.gov/pubmed/11441208

It does lower body temperature in normothermic people but by any average 0.3C (range 0.1-0.6C).  I would guess that i the pain/injury/illness that you are taking the paracetamol for, is going to slow you down, which would presumably result in you getting colder quicker, so you need to weigh the two things against each other.

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pneame - on 14 May 2019
In reply to The Potato:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1403265/ 

Liver toxicity. Also prone to causing rebound headaches (you stop taking it, get a headache, take some, headache gets better, stop taking it.... etc etc.)

Fairly safe at recommended dose and when not used on a daily basis. 

Doesn't exactly answer your question but you don't say why you are taking it. 

Post edited at 14:17
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dunc56 - on 14 May 2019
In reply to The Potato:

some evidence now that Paracetamol does not decrease body temperature .....

https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD003676/epdf/standard

Other refs available.  

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Lornajkelly - on 14 May 2019
In reply to The Potato:

As I understand it, your temperature is raised during fever because of a protein called pyrogen, which starts a cascade that causes the hypothalamus to increase the body's temperature.  Paracetamol inhibits the pyrogen so that it doesn't cause the increase.  I think it doesn't normally reduce your body temperature outside of fever, or maybe a similar mechanism during hot weather, as you say in your post (but I've never heard this so I can't say).  

As pneame said, liver toxicity and CPDH (chronic persistent daily headache).  Just don't overdose and you'll be fine.  

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Deadeye - on 14 May 2019
In reply to The Potato:

Are you taking it for pain relief from temporary condition? For pain relief from a chronic one? Or for some misplaced idea that it I'll be performance enhancing for your swim?

Different answers.

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The Potato - on 14 May 2019

Thank you all for very varied responses, no wonder I couldnt work it out myself.

Pyrogen, interesting, never heard of that one, might look in to it a bit more out of curiosity.

Its for an recent pain ive got in my throat, doesnt seem to be going away and Ive got a triathlon at the weekend. Waiting to see ENT doc about it but in the meantime.... the show must go on.

Post edited at 19:57
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pneame - on 14 May 2019
In reply to Lornajkelly:

> Just don't overdose and you'll be fine.  

And this can be easier said than done - I was given a prescription for percocet recently and thought "ah yes, opioids, better be careful with those". On looking at the fine print, I saw that it included acetaminophen (aka paracetamol). As do quite a few other things.

Opioids are the bees knees.....

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Timmd on 14 May 2019
In reply to The Potato:

Should you be doing a triathlon with a sore throat?

Edit: Experience has taught me that illness and exercise don't generally go together so well. 

Post edited at 21:35
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summo on 14 May 2019
In reply to The Potato:

> Its for an recent pain ive got in my throat, ..........the show must go on.

There could be a connection? Training hard, limited recovery? Busy outside training? Rested heart rate higher than normal?

You might not need drugs, but a couple of days rest. 

Post edited at 21:48
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bonebag - on 14 May 2019
In reply to The Potato:

Have you tried Ibuprofen for your throat? If the pain is caused by inflammation Ibuprofen may be better. It's designed to be an anti-inflammatory.  Paracetamol isn't anti-inflammatory. It is an analgesic and controls pain by a different mechanism. 

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Timmd on 14 May 2019
In reply to summo: Thanks for saying what I was thinking, but which got scrambled between my brain and my fingers.

Post edited at 22:26
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the sheep - on 14 May 2019
In reply to pneame:

> Opioids are the bees knees.....

Cocodamol high strength has helped with pain but never noticed an effect when diving in cold water 

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The Potato - on 09:53 Wed

in reply to all -

Should you be doing a triathlon with a sore throat?

depends if its an infection or not, I dont think it is....

You might not need drugs, but a couple of days rest. 

already had two weeks off sadly.....

Have you tried Ibuprofen for your throat? 

please re read my post - no nsaids

Cocodamol high strength has helped with pain but never noticed an effect when diving in cold water

Thats reassuring to know thanks 

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summo on 10:21 Wed
In reply to The Potato:

I presume you've or ideally a doctor have ruled out stomach related issues like acid reflux etc. 

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Eric9Points - on 19:02 Wed
In reply to pneame:

> Opioids are the bees knees.....

Did you know they kill 130 people a day in the USA?

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pneame - on 19:46 Wed
In reply to Eric9Points:

> Did you know they kill 130 people a day in the USA?

Indeed - but they are really effective for knocking out pain! Slightly worse than the gun and vehicular death rates per day (~100 a day off the top of my head for each). 

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